Search on: S-PHASE KINASE-ASSOCIATED PROTEINS 
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Descriptor English:   S-Phase Kinase-Associated Proteins 
Descriptor Spanish:   Proteínas Quinasas Asociadas a Fase-S 
Descriptor Portuguese:   Proteínas Quinases Associadas a Fase S 
Tree Number:   D12.776.157.743
Definition English:   A family of structurally-related proteins that were originally identified by their ability to complex with cyclin proteins (CYCLINS). They share a common domain that binds specifically to F-BOX MOTIFS. They take part in SKP CULLIN F-BOX PROTEIN LIGASES, where they can bind to a variety of F-BOX PROTEINS. 
History Note English:   2004; use S-PHASE KINASE ASSOCIATED PROTEINS (NM) 1983-2003; for P19(SKP1)PROTEIN and P45(SKP) PROTEIN use S-PHASE KINASE ASSOCIATED PROTEINS (NM) 1995-2003; for P45(SKP) use UBIQUITIN-PROTEIN LIGASES (NM) 1999-2003 
Allowable Qualifiers English:  
administration & dosage adverse effects
agonists antagonists & inhibitors
analysis biosynthesis
blood cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
drug effects diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
ultrastructure urine
Record Number:   38256 
Unique Identifier:   D044786 

Occurrence in VHL:
 

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